To meet the Sustainable Development Goals (SDGs) by 2030, we need to accelerate, scale, and sustain progress on a wide range of challenges. Companies have critical roles to play. But whether and to what extent they can actively contribute to solving these challenges depends on their business ecosystems. Business ecosystems are communities or networks of interconnected, interdependent players whose actions help determine what companies must do to be profitable and competitive. Do they have the right incentives, investment, information, and implementation support? To unleash companies’ full power to help achieve our shared goals, their business ecosystems must make doing the right thing for development the best thing for business. This report shows how to develop business ecosystems for impact.